Amicrobial pustulosis of the folds. A cutaneous manifestation associated with connective tissue disease |
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Authors: | MP Stefanidou PE Kanavaros KS Stefanaki AD Tosca |
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Affiliation: | Department of Dermatology, Division of Medicine, University of Heraklion, Greece. |
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Abstract: | Amicrobial pustulosis (AP) is a recently defined entity associated with connective tissue diseases. Few cases have appeared in the literature. We report a case of AP coexisting with a systemic lupus erythematosus-scleroderma overlap syndrome and marked photosensitivity. The patient presented prominent pustular skin lesions and a few discoid lupus ones. No significant differences in the inflammatory infiltrate were found between the two clinical variants. The infiltrate consisted mainly of CD4+ lymphocytes and many neutrophils. CD1a+ dendritic cells were few in both epidermis and dermis. AP introduces a potential source of diagnostic confusion, but increasing experience of this syndrome will improve the awareness and diagnostic potential among dermatologists. |
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