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Genes Possessing the Most Frequent DNA DSBs Are Highly Associated with Development and Cancers,and Essentially Overlap with the rDNA-Contacting Genes |
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| Authors: | Nickolai A Tchurikov Ildar R Alembekov Elena S Klushevskaya Antonina N Kretova Ann M Keremet Anastasia E Sidorova Polina B Meilakh Vladimir R Chechetkin Galina I Kravatskaya Yuri V Kravatsky |
| Affiliation: | 1.Department of Epigenetic Mechanisms of Gene Expression Regulation, Engelhardt Institute of Molecular Biology Russian Academy of Sciences, 119334 Moscow, Russia; (I.R.A.); (E.S.K.); (A.N.K.); (A.M.K.); (A.E.S.); (P.B.M.); (V.R.C.); (G.I.K.); (Y.V.K.);2.Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology Russian Academy of Sciences, 119334 Moscow, Russia |
| Abstract: | |
| Keywords: | DNA double strand breaks (DSBs) whole-genome analysis 4C-rDNA rDNA-contacting genes HEK293T epigenetics differentiation morphogenesis cancers |