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General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants |
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| Authors: | L Serfass PJ Casara |
| Affiliation: | Marion Merrell Dow, Strasbourg, France. |
| Abstract: | Stereospecific synthesis of cis and trans 3-substituted vinyl-gamma-aminobutyric acid analogs were obtained by either a Claisen rearrangement or a Wittig reaction from common diene precursors. |
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