酰胺键为间隔基的吡啶双子表面活性剂合成及性能

以乙二胺、1-溴代烷、氯乙酰氯和吡啶为原料,经卤代、酰胺化和季铵化反应合成了系列酰胺键为间隔基的吡啶双子表面活性剂。目标产物合成条件:超声波(40kHz,100W)辅助反应,反应温度60℃,反应时间5h。用 FTIR、¹H NMR、¹³C NMR对目标产物进行了结构表征,对目标产物的临界胶束浓度(cmc)、乳化性、泡沫稳定性和杀菌性能进行了考察。实验结果表明,该系列产物的临界胶束浓度cmc 为1.4×10^-2～2.3×10^-5mol/L,具有较好的乳化性和稳泡性。在浓度为100mg/L时,烷基链碳原子数为8的表面活性剂对大肠杆菌和枯草芽孢杆菌的抑菌效果最好。

Synthesis and properties of pyridine Gemini surfactants containing amide spacer

Pyridine Gemini surfactant containing amide spacer was synthesized using ethylenediamine, 1-bromoalkane, chloroacetyl chloride and pyridine as raw materials by halogenation amidation reaction and quaterisation. The target product synthesis condition is as following:ultrasonic for assisting reaction was 40kHz and 100W, reaction temperature was 60℃, and reaction time was 5h. The target products were characterized by FTIR, ¹H NMR and ¹³C NMR. The major performance of target products was investigated, including critical micelle concentration and bactericidal property. The results show that the cmc of target product is 1.4×10^-2～2.3×10^-5mol/L, and has a good emulsification and stability. The antibacterial effect of surfactant with eight carbon alkyl chains for escherichia coli and bacillus subtilis is the best.