脱氢枞胺及其衍生物的应用研究进展

脱氢枞胺是歧化松香胺的主要成分,具有三环菲骨架结构,是松香重要的改性产品之一。本文综述了脱氢枞胺及其衍生物的应用研究进展,包括脱氢枞胺在手性化合物分离方面的应用和脱氢枞胺衍生物在抑菌、防腐、缓蚀、金属离子浮选、催化、抗癌、抗氧化、抗溃疡、可与雄性激素结合等方面的应用。指出目前脱氢枞胺成盐衍生物及脱氢枞胺N-C衍生物的研究较为广泛,脱氢枞胺B环和C环改性衍生物的研究仍需加强,而且对于B环和C环改性衍生物的深入研究,将进一步促进脱氢枞胺衍生物在生物活性方面的应用。最后对脱氢枞胺衍生物在生物医学工程上的应用前景进行了展望。

Research progress in the application of dehydroabietic amine and its derivatives

As the main component of disproportionated rosin amine, dehydroabietylamine with the tricyclic diterpene skeleton is one of the important modified products of rosin. The research progress in the application of dehydroabietylamine and its derivatives is reviewed, including the application of dehydroabietylamine in chiral compound separation and the application of dehydroabietylamine derivatives in antibacterial, anticorrosion, corrosion inhibition, metal ion flotation, catalysis, anticancer, antioxidation, antiulcer and combining with testosterone. At present, the study of dehydroabietylamine derivatives modified on B ring and C ring is still needed to be strengthened although dehydroabietic amine salts and N-C derivatives are widely studied. And furthermore, the in-depth study of dehydroabietylamine derivatives modified on B ring and C ring will further promote the application of dehydroabietylamine derivatives in biological activity. The future research and application of dehydroabietic amine derivatives on biomedical engineering are previewed.