Fabrication of porous polylactic acid films assisted by dip‐coating and template leaching techniques |
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| Authors: | Ta‐I Yang Tai‐Lun Su Po‐Liang Lin I‐Hsiang Tseng Chih‐Hung Chang Hsu‐Wei Fang |
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| Affiliation: | 1. Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan;2. Department of Chemical and Materials Engineering, National Chin‐Yi University of Technology, Taichung, Taiwan;3. Division of Orthopedics, Department of Surgery, Far Eastern Memorial Hospital, Banciao, New Taipei City, Taipei, Taiwan;4. Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Chungli, Taoyuan, Taiwan;5. Division of Medical Engineering Research, National Health Research Institutes, Miaoli, Taiwan |
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| Abstract: | A new simple method was developed to fabricate porous polylactic acid (PLA) films coated directly on substrates. The PLA films with a controllable thickness were realized using a dip‐coating technique. The pore structure of the resulting porous PLA films was tailored by utilizing phase inversion process and template leaching techniques. The experimental results show that the resulting PLA films became thicker when using the coating solution with a higher viscosity or applying a faster withdrawal speed. The porous structures (pore size and void density) of the resulting PLA films are significantly influenced by the polymer concentration, the nonsolvents, and the addition of poly(ethylene glycol) templates. The analyses of solubility parameters was utilized to explain the porous structures of the resulting PLA films in details. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012 |
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| Keywords: | polylactic acid porous thin film dip coating template leaching biomaterial |
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