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Continuous fluidized bed drying: Residence time distribution characterization and effluent moisture content prediction
Authors:Hao Chen  Emily Diep  Timothy A G Langrish  Benjamin J Glasser
Affiliation:1. Department of Chemical and Biochemical Engineering, Rutgers University, Piscataway, New Jersey;2. School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, New South Wales, Australia
Abstract:The mixing and drying behavior in a continuous fluidized bed dryer were investigated experimentally by characterizing the residence time distribution (RTD) and incorporating a micromixing model together with the drying kinetics obtained from batch drying. The RTD of the dryer was modeled using a tank-in-series model. It was found that a high initial material loading and a low material flow rate resulted in a reduced peak height and broaded peak width of the RTD curve. To predict the continuous dryer effluent moisture content, we combined: (a) the drying kinetics as determined in a batch fluidized bed dryer, (b) the RTD model, and (c) micromixing models—segregation and maximum mixedness models. It was found that the segregation model overpredicted the effluent moisture content by up to 5% for the cases we have studied while the maximum mixedness model gave a good prediction of the effluent moisture content.
Keywords:pharmaceutical continuous manufacturing  fluidized bed drying  residence time distribution  moisture measurement
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