Heavy metals accumulation effect in rabbit body fluids after smoking |
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Authors: | Kuang-biao Zhong Ming Gui Li-yong Zhu Wei Li Cha-xiang Guan and Fang-qiu Guo |
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Affiliation: | (1) National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan |
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Abstract: | Concentration of heavy metals in blood and urine of rabbit after inhaling three different kinds of cigarette was studied through
the animal passive smoking pattern. The samples were prepared by nitric acid solution digestion and determination of seven
kinds of heavy metals including Hg, Se, Sn, Pb, Cd, Ni and Cr was performed by inductively coupled plasma-atomic emission
spectrometry (ICP-AES). The ICP-AES method was established with good precision and accuracy, relative standard deviation (n=6) was between 2.9% and 5.9%, and the recovery was in the range of 95.0%–104.2%. Concentration of six heavy metals increases
in some extent in blood and urine after period of smoking and the increasing of heavy metals in blood and urine all shows
time dependence. Significantly higher heavy metal levels are observed in the blood and urine of the cigarette inhaling rabbits
in the exposed group. The concentration of six kinds of heavy metals in the blood of the rabbit increases after 16 weeks exposing
to cigarette smoking. Three times of Hg, ten times of Se and trace amount of Pb, Cd, Ni and Cr are detected in the blood after
16 weeks of smoking. For urine samples, about three times of Hg, two times of Se, five times of Pb and trace amount of Cd
are detected after 16 weeks of inhalation of cigarette. Comparatively, higher concentration of heavy metals are detected after
inhaling of Nise cigarette. |
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Keywords: | inductively coupled plasma-atomic emission spectrometry blood urine heavy metal element |
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