Blood flow driven by surface tension in a microchannel

This study aims to identify distinct blood flow characteristics in a microchannel at different sloping angles. The channel is determined by a bottom hydrophilic stripe on a glass substrate and a fully covered hydrophobic glass substrate. The channel has a height of 3 μm, and a width of 100 μm. It is observed that increasing the sloping angle from −90° (downward flow) to 90° (upward flow) increases the blood flow rate monotonically. These peculiar behaviors on the micro scale are explained by a dynamic model that establishes the balance among the inertial, surface tension, gravitational, and frictional forces. The frictional force is further related to the effective hematocrit. The model is used to calculate the frictional force, and thus the corresponding hematocrit, which is smaller when the blood flows upward, reducing the frictional force.