Production of a high purity F radioactive beam |
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Authors: | M Cogneau P Decrock M Gaelens D Labar P Leleux M Loiselet G Ryckewaert |
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Affiliation: | a Centre de Recherches du Cyclotron,Unité de Tomographie par Positrons and Institut de Physique Nucléaire, Université Catholique de Louvain, Chemin du Cyclotron 2, B-1348 Louvain-la-Neuve, Belgium;b Instituut voor Kern- en Stralingsfysica, Katholieke Universiteit Leuven, B-3001 Leuven, Belgium |
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Abstract: | An efficient method for the production and post-acceleration of a pure 18F(T1/2=109.8 min) radioactive beam has been developed. Large amounts of 18F are produced via the 18O(p,n)18F reaction using a 15.5 MeV proton beam on an 18O-enriched water target. After the chemical purification of the target content, the 18F activity is transferred into 18F]-fluoromethane. It is then transported to an ECR ion source, where after dissociation of the molecules, the fluorine atoms are ionized. Finally, the 18F2+ ions are accelerated to 14 MeV in a second cyclotron. The different steps in the production cycle and the characteristics of the final 18F beam are discussed. |
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Keywords: | 18F Radioactive ion beam [18F]-fluoromethane synthesis ECR ion source Isobaric separation |
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