Electron microscopic study of the myocardium of mice with experimental infection caused by Coxsackie virus A13

Diffuse myocarditis with alteation and proliferation was described in adult BALB/c mice infected with Coxsacke A13 virus. A marked tendency to sclerotic processes 30 to 60 days after the infection was noted; this can underly the reduction of the functional activity of the myocardium and lead to the development of cardiomyopathy.