| 离子型~(211)At致体外艾氏腹水癌细胞超微结构的改变 |
| |
| 引用本文： | 刘侠,王子淑,王喜忠,陈文元. 离子型~(211)At致体外艾氏腹水癌细胞超微结构的改变[J]. 核技术, 1991, 0(11) |
| |
| 作者姓名： | 刘侠 王子淑 王喜忠 陈文元 |
| |
| 作者单位： | 四川大学(刘侠，王子淑，王喜忠)，四川大学(陈文元) |
| |
| 摘 要： | 报道离体培养的小鼠艾氏腹水癌细胞用37—222kBq/ml的离子型~(221)At分四个剂量处理,透射电镜观察,发现细胞内膜系统受到严重辐射损伤。剂量越大,损伤越严重。辐射敏感的靶部位为细胞核(核膜)、线粒体,其形态变化最为显著。
|
| 关 键 词： | 离子型~(211)At 艾氏腹水癌细胞 超微结构 辐射损伤 |
Ultrastructural changes of Ehrlich ascites cells induced by ionic 211At in vitro |
| |
| Liu Xia Wang Zishu Wang Xizhong Chen Wenyuan. Ultrastructural changes of Ehrlich ascites cells induced by ionic 211At in vitro[J]. Nuclear Techniques, 1991, 0(11) |
| |
| Authors: | Liu Xia Wang Zishu Wang Xizhong Chen Wenyuan |
| |
| Affiliation: | Sichuan University |
| |
| Abstract: | Cultured Ehrlich ascites cells were treated with ionic 211At in vitro and observed with transmission electron microscopy. It was found that the endomembrane system of the cells was injured seriously. The injury severity was increased with increase of 211At (ionic) dose. Radiation sensitive sites in the cell were nuclei and mitochondria. |
| |
| Keywords: | Ionic 211At Ehrilich ascites cells Ultrastructure Radiation injury |
| 本文献已被 CNKI 等数据库收录！ |
