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Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties |
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| Authors: | Kalla Reddi Mohan Naidu Shaik Ibrahim Khalivulla Syed Rasheed Sharida Fakurazi Palanisamy Arulselvan Ola Lasekan Faridah Abas |
| Abstract: | Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated. |
| Keywords: | cytotoxicity properties bisindolylmethanes dibisindolylmethanes green catalyst |