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Copper phthalocyanine catalysis to oxidation of adrenaline by oxygen and its application in adrenaline detection
Authors:Jun Huang  Mingtian Li  Yan Tang  Hua Fang  Liyun Ding
Affiliation:Key Laboratory of Fiber Optic Sensing Technology and Information Processing of Ministry of Education, Wuhan University of Technology, Wuhan 430070, China
Abstract:The oxidation of adrenaline by dioxygen using copper phthalocyanine (CuPc) as the catalyzer was studied. CuPc has the optimal catalytic pH of 8.0 and the optimal catalytic temperature of 55 ℃. It also has good storage and operation stability. The fiber optic adrenaline biosensor based on CuPc catalysis and fluorescence quenching was fabricated and studied. This sensor has the detection range of 7.0×10-5 -1.5×10-4 mol/L, the response time of 4 min, good reproducibility and stability.
Keywords:CuPc  catalytic oxidation  mimic enzyme  fiber optic adrenaline sensor
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