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| 壳寡糖及其溴络合物的抗菌活性研究 | |
| 引用本文： | 冯文娟,马韵升,徐泽平,刘结磊,孙建忠.壳寡糖及其溴络合物的抗菌活性研究[J].中国酿造,2015,34(7):56. |
| 作者姓名： | 冯文娟 马韵升 徐泽平 刘结磊 孙建忠 |
| 作者单位： | 1.黄河三角洲京博化工研究院有限公司，山东滨州256500；2.山东京博控股股份有限公司，山东滨州256500； 3.滨州市环境微生物技术工程研究中心，山东滨州256500 |
| 基金项目： | 山东省技术创新项目（201510516008） |
| 摘 要： | 采用培养基稀释法测定壳寡糖及其溴络合物的最小抑菌浓度（MIC）和最小杀菌浓度（MBC），研究壳寡糖及其溴络合物的抗菌活性。结果表明，壳寡糖对大肠杆菌的MIC和MBC均为6.5 g/L；对白色念珠菌的MIC为4.0 g/L，MBC为8.0 g/L；对枯草芽孢杆菌的MIC和MBC均为1.5 g/L。壳寡糖溴络合物对大肠杆菌的MIC为1.0 g/L，MBC为1.2 g/L；对白色念珠菌的MIC为1.5 g/L，MBC为2.0 g/L；对枯草芽孢杆菌的MIC为1.0 g/L，MBC为1.5 g/L。与壳寡糖相比，壳寡糖溴络合物对大肠杆菌、白色念珠菌和枯草芽孢杆菌的抑菌效果更好。 |
| 关 键 词： | 壳寡糖 壳寡糖溴络合物 抗菌活性 |
Antibacterial activity of oligochitosan and its bromide complexes |
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| FENG Wenjuan,MA Yunsheng,XU Zeping,LIU Jielei,SUN Jianzhong.Antibacterial activity of oligochitosan and its bromide complexes[J].China Brewing,2015,34(7):56. | |
| Authors: | FENG Wenjuan MA Yunsheng XU Zeping LIU Jielei SUN Jianzhong |
| Affiliation: | 1.Yellow River Delta JingBo Research Institute of Chemical Industry Co., Ltd., Binzhou 256500, China; 2.Shandong Chembroad Holding Co., Ltd., Binzhou 256500, China; 3.Binzhou Environmental Microbial Technology and Engineering Research Center, Binzhou 256500, China |
| Abstract: | To investigate the inhibitory effect of oligochitosan and its bromide complexes, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of oligochitosan and its bromide complexes was measured by medium dilution method. The results showed that the MIC and MBC of oligochitosan on Escherichia coli was 6.5 g/L; the MIC of oligochitosan on Candida albicans was 4.0 g/L, the MBC was 8.0 g/L; the MIC and MBC of oligochitosan on Bacillus subtilis was 1.5 g/L. The MIC of oligochitosan bromide complexes on E. coli was 1.0 g/L, the MBC was 1.2 g/L; the MIC on Candida albicans was 1.5 g/L, the MBC was 2.0 g/L; the MIC on Bacillus subtilis was 1.0 g/L, the MBC was 1.5 g/L. Compared with chitosan, the antibacterial activity of oligochitosan bromide complexes on E. coli, C. albicans and B. subtilis was better. |
| Keywords: | oligochitosan oligochitosan bromide complexes inhibitory effect |
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