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Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans |
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| Authors: | Sarah C Good Katherine M Dewison Sheena E Radford Patricija van Oosten-Hawle |
| Affiliation: | Faculty of Biological Sciences, School of Molecular and Cell Biology & Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK; (S.C.G.); (K.M.D.); (S.E.R.) |
| Abstract: | |
| Keywords: | β 2 microglobulin systemic amyloidosis protein misfolding C elegans extracellular ER stress UPRER proteotoxicity stress response |