| 蚕蛹蛋白多肽对小鼠免疫调节作用的研究 |
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| 引用本文： | 戚颖欣,孟 军,曹柏营,费保亮,闻其龙. 蚕蛹蛋白多肽对小鼠免疫调节作用的研究[J]. 食品科学, 2009, 30(23): 419-421. DOI: 10.7506/spkx1002-6300-200923094 |
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| 作者姓名： | 戚颖欣 孟 军 曹柏营 费保亮 闻其龙 |
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| 作者单位： | 1.吉林工程技术师范学院食品工程学院 2.吉林省通化市食品药品检验所 |
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| 基金项目： | 吉林省教育厅计划项目(吉教科合字第(2009233)号) |
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| 摘 要： | 实验观察蚕蛹蛋白多肽对小鼠的免疫调节作用。实验将蚕蛹蛋白多肽分为高、中、低剂量组，分别为5.0、1.7、0.6g/kg bw·d 喂饲小鼠40d，观察小鼠免疫器官指数变化、迟发型变态反应(DTH)、抗体生成细胞数和碳廓清能力等4 个实验项目。实验结果表明：与阴性对照组比较，蚕蛹蛋白多肽能显著增加小鼠胸腺指数，增加小鼠足跖肿胀度，增加小鼠抗体细胞生成数量，增加单核- 巨噬细胞吞噬能力。说明蚕蛹蛋白多肽具有明显的免疫调节作用。
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| 关 键 词： | 蚕蛹蛋白 多肽 免疫调节 |
| 收稿时间： | 2009-08-24 |
Immunoregulation Functions of Pupa Polypeptides in Mice |
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| QI Ying-xin,MENG Jun,CAO Bai-ying,FEI Bao-liang,WEN Qi-long. Immunoregulation Functions of Pupa Polypeptides in Mice[J]. Food Science, 2009, 30(23): 419-421. DOI: 10.7506/spkx1002-6300-200923094 |
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| Authors: | QI Ying-xin MENG Jun CAO Bai-ying FEI Bao-liang WEN Qi-long |
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| Affiliation: | 1. College of Food Engineering, Jilin Teachers’Institute of Engineering and Technology, Changchun 130052, China；2. Institute for Food and Drug Control of Tonghua City of Jilin Province, Tonghua 134000, China |
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| Abstract: | In order to investigate immunoregulation functions of pupa polypeptides, mice were randomly divided 3 groups and conducted to oral administration of pupa polypeptides at the doses of 5.0, 1.7 g/kg·d and 0.6 g/kg·d for 40 days, respectively. Changes in immune organ index, delayed-type hypersensitivity (DTH), number of antibody-producing cells and carbon clearance capability were examined to evaluate immune functions. Results indicated that pupa polypeptides could significantly improve thymus index, promote plantar swelling, increase the generation of antibody-producing cells and enhance capability of monocyte-macrophage phagocytosis. Therefore, pupa polypeptides exhibited a significant effect on improvement of immune functions in mice. |
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| Keywords: | pupa protein polypeptide immunoregulation effect |
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