| 拟除虫菊酯类农药在超临界流体色谱中的对映体分离 |
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| 引用本文： | 徐明仙,高伟亮,金丽霞,马斌斌,林春绵. 拟除虫菊酯类农药在超临界流体色谱中的对映体分离[J]. 农药, 2011, 50(7) |
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| 作者姓名： | 徐明仙 高伟亮 金丽霞 马斌斌 林春绵 |
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| 作者单位： | 1. 杭州职业技术学院,临江学院,杭州,310018
2. 浙江工业大学,生物与环境工程学院,杭州,310032 |
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| 基金项目： | 浙江省自然科学基金项目(Y506264) |
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| 摘 要： | [目的]获得单一对映体对于低毒高效的农药生产和环境安全具有重要意义。[方法]使用超临界CO2色谱,对6种拟除虫菊酯类农药在Sino-Chiral OJ柱上进行对映体分离研究,考察了改性剂种类(甲醇、乙醇和异丙醇)及体积分数(1%、3%、5%)对其分离的影响。[结果]高效氯氟氰菊酯在3种改性剂条件下都得到了基线分离;氯菊酯只在甲醇作为改性剂时得到分离;氰戊菊酯只在3%乙醇改性条件下实现部分分离;氯氰菊酯在乙醇作为改性剂时取得了最优分离,得到8个异构体中的7个出峰;联苯菊酯和溴氰菊酯均只得到2个对映体出峰。[结论]在手性分离过程中,对映体与手性固定相之间的偶极-偶极和π-π作用对菊酯类农药的分离起较大作用,同时卤素取代基的电负性大小对分离也有较大影响。
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| 关 键 词： | 拟除虫菊酯 超临界色谱 对映体分离 Sino-ChiralOJ柱 |
Enantiomer Separation of Synthetic Pyrethroids by Supercritical Fluid Chromatography |
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| XU Ming-xian,GAO Wei-liang,JIN Li-xia,MA Bin-bin,LIN Chun-mian. Enantiomer Separation of Synthetic Pyrethroids by Supercritical Fluid Chromatography[J]. Pesticides, 2011, 50(7) |
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| Authors: | XU Ming-xian GAO Wei-liang JIN Li-xia MA Bin-bin LIN Chun-mian |
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| Affiliation: | XU Ming-xian1,GAO Wei-liang2,JIN Li-xia2,MA Bin-bin2,LIN Chun-mian2(1.Lin-jiang College,Hangzhou Vocational,Technical College,Hangzhou 310018,China,2.College of Biological,Environmental Engineering,Zhejiang University of Technology,Hangzhou 310032,China) |
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| Abstract: | To obtain the pure-enantiomer of chiral pesticides is meaningful for researching their stereoselectivity of pesticidal activity and toxicity to environmental fate.[Methods] The enantiomer separation of synthetic pyrethroids was conducted on Sino-Chiral OJ by supercritical fluid chromatography(SFC).The influence of the type and concentration of organic modifier in mobile phase was studied.[Results] Lambda-cyhalothrin could be separated with 1-5% methanol,ethanol or isopropanol in supercritical CO2.Permethrin... |
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| Keywords: | synthetic pyrethroids supercritical fluid chromatography enantiomeric separation Sino-Chiral OJ |
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