The effect of aluminum hydroxide dissolution on the bleeding of aluminum lake dyes |
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| Authors: | A Desai GE Peck JE Lovell JL White SL Hem |
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| Affiliation: | Department of Industrial and Physical Pharmacy, Purdue University, West Lafayette, Indiana 47907. |
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| Abstract: | The effect of pH on the bleeding of FD&C yellow No. 5 aluminum lake and FD&C red No. 40 aluminum lake was investigated. The pH-bleeding profiles corresponded to the pH-solubility profile of aluminum hydroxide. The similarity of the bleeding profiles of both lake dyes and the pH-solubility profile of aluminum hydroxide indicates that pH related bleeding, other than that occurring by competition with anions, is a result of dissolution of the aluminum hydroxide substrate. This dissolution is related to the properties of the substrate rather than to the structure of adsorbed dye. |
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