The human homologue of the retroviral oncogene qin maps to chromosome 14q13 |
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| Authors: | K Kastury J Li T Druck H Su PK Vogt CM Croce K Huebner |
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| Affiliation: | Jefferson Cancer Institute, Jefferson Medical College, Philadelphia, PA 19107. |
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| Abstract: | Chromosomal mapping of the human QIN gene (renamed FKH2 by the Human Genome Organization Nomenclature Committee) was initially accomplished by correlation of the presence of the QIN locus with specific chromosome regions in a rodent-human hybrid panel. This analysis revealed that the human QIN gene maps to chromosome region 14q11.2-->14q32, between the TCR and IGH loci. Further analysis by fluorescence in situ hybridization techniques with a human QIN genomic clone refined the human QIN gene localization to 14q13. |
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