| 生物活性天然产物分离技术的研究进展(英文) |
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| 引用本文： | 任其龙,邢华斌,鲍宗必,苏宝根,杨启炜,杨亦文,张治国.生物活性天然产物分离技术的研究进展(英文)[J].中国化学工程学报,2013,21(9):937-952. |
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| 作者姓名： | 任其龙 邢华斌 鲍宗必 苏宝根 杨启炜 杨亦文 张治国 |
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| 作者单位： | Key Laboratory of Biomass Chemical Engineering of Ministry of Education,Department of Chemical and Biological Engineering,Zhejiang University |
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| 基金项目： | Supported by the National Natural Science Foundation of China(20936005,21076175 and 21076178);the National High Technology Research and Development Program of China(2012AA040211);the Program for Zhejiang Leading Team of S&T Innovation(2011R50002) |
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| 摘 要： | Bioactive natural products are a main source of new drugs, functional foods and food additives. The separation of bioactive natural products plays an important role in transformation and use of biomass. The isolation and purification of bioactive_principle from a complex matrix is often inherent bottleneck for the utilization of natural products, so a series of extraction and separation techniques have been developed. This review covers recent advances in the separation of bioactive natural products with an emphasis on their solubility and diffusion coefficients, recent extraction techniques and isolation techniques. This overview of recent technological advances, dis- cussion of pertinent problems and prospect of current methodologies in the separation of bioactive natural products may provide a driving force for development of novel separation techniques.
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| 关 键 词： | 天然产物 生物活性 分离技术 提取技术 食品添加剂 功能食品 扩散系数 隔离技术 |
| 收稿时间： | 17 March 2013 |
Recent Advances in Separation of Bioactive Natural Products |
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| REN Qilong;XING Huabin;BAO Zongb;SU Baogen;YANG Qiwei;YANG Yiwen;ZHANG Zhiguo.Recent Advances in Separation of Bioactive Natural Products[J].Chinese Journal of Chemical Engineering,2013,21(9):937-952. |
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| Authors: | REN Qilong;XING Huabin;BAO Zongb;SU Baogen;YANG Qiwei;YANG Yiwen;ZHANG Zhiguo |
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| Affiliation: | REN Qilong;XING Huabin;BAO Zongb;SU Baogen;YANG Qiwei;YANG Yiwen;ZHANG Zhiguo;Key Laboratory of Biomass Chemical Engineering of Ministry of Education,Department of Chemical and Biological Engineering,Zhejiang University; |
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| Abstract: | Bioactive natural products are a main source of new drugs, functional foods and food additives. The separation of bioactive natural products plays an important role in transformation and use of biomass. The isolation and purification of bioactive principle from a complex matrix is often inherent bottleneck for the utilization of natural products, so a series of extraction and separation techniques have been developed. This review covers recent advances in the separation of bioactive natural products with an emphasis on their solubility and diffusion coefficients, recent extraction techniques and isolation techniques. This overview of recent technological advances, discussion of pertinent problems and prospect of current methodologies in the separation of bioactive natural products may provide a driving force for development of novel separation techniques. |
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| Keywords: | biomass chromatography extraction isolation natural products |
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