A prototype system to measure X-ray absorption spectra for diagnosis in vivo |
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Affiliation: | 1. LIBPhys-UNL, DF, FCT, Universidade NOVA de Lisboa, 2829-516 Monte da Caparica, Portugal;2. IPFN, IST-UL, Campus Tecnológico e Nuclear, E.N. 10, 2695-066 Sacavém, Portugal;3. C2TN, IST-UL, Campus Tecnológico e Nuclear, E.N. 10, 2695-066 Sacavém, Portugal;1. Department of Computer Science, Università degli Studi di Milano, Via Bramante, 65, 26013 Crema, Italy;2. Department of Physics, Università degli Studi di Milano, Milan, Via Celoria, 16, 20133 Milan, Italy;3. I.N.F.N. Milano, Via Celoria, 16, 20133 Milan, Italy;4. Department of Computer Engineering, Maltepe University, Marmara E?itim Köyü, 34857 Maltepe-Istanbul, Turkey;5. Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Piazza Leonardo da Vinci, 32, 20133 Milan, Italy;1. Beijing Key Lab for Precision Optoelectronic Measurement Instrument and Technology, School of Optoelectronics, Beijing Institute of Technology, Beijing 100081, China;2. School of Instrumentation Science and Opto-electronics Engineering, Beihang University, Beijing 100191, China |
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Abstract: | We presented a new non-destructive test system for recording of X-ray absorption spectra. Its purpose was to investigate X-ray absorption spectral characteristics of organic and inorganic compounds and to explore the potential for biomedical pathological examination in vivo. An X-ray source with a maximum voltage of 80 kV and maximum current of 1 mA was selected for both good penetration and low radiation dose. A cadmium telluride (CdTe) detector was chosen for its wide energy range. Pulse-height analysis of the output of this sensor yielded energy spectra of X-rays that had passed through the sample. We calibrated the sensor with varying X-ray tube voltages and used tungsten X-ray lines to verify its accuracy. Different kinds of powders, aqueous solutions, aluminium alloys, and plastics were used as experimental samples to show their X-ray spectral absorption differences. The instrument had good prospects for further diagnostics combining radiology and tissue optics. |
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Keywords: | X-ray absorption spectrum Diagnostic testing In vivo Radiation Prototype |
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