|
|||||
|
|
Mechanical Properties of Porous Polylactide/Chitosan Blend Membranes |
|
| Authors: | Ying Wan Quan Wu Sheng Wang Shengmin Zhang Zhilin Hu |
| Affiliation: | 1. Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, 430074, ChinaAdvanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, 430074, China.;2. Department of Chemistry and Chemical Engineering, Royal Military College of Canada, PO Box 17000, Station Forces, Kingston K7K 7B4, Ontario, Canada;3. Advanced Biomaterials and Tissue Engineering Center, Huazhong University of Science and Technology, Wuhan, 430074, China;4. Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106, USA |
| Abstract: | Porous membranes were fabricated using chitosan and poly(DL ‐lactide) or poly(L ‐lactide) blends through a combinatorial technique. Well‐controlled porous structures could be achieved by optimizing processing conditions. The ductility and toughness of dry porous membranes were improved by incorporating an increased amount of chitosan, and the physical strength and dimensional stability of hydrated porous membranes were preserved if the components were used in a suitable ratio. Although there were measurable differences in the pore‐size distributions of membranes with the same composition prepared under identical conditions, this showed no effect in their dry states.  |
| Keywords: | chitosan mechanical property polylactide porous blend membrane |