Langerhans cell histiocytosis |
| |
| Authors: | Mde L Chauffaille RM Valério CM Diniz MM Sim?es S Enokihara N Michalany KV Ferreira JA Martinez KM Hassun AN Atallah J Kerbauy |
| |
| Affiliation: | Disciplina de Hematologia e Hemoterapia, Escola Paulista de Medicina, Universidade Federal de S?o Paulo, Brazil. |
| |
| Abstract: | The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentin, but the diagnosis was done with the demonstration of Birbeck granules with electronic microscopy. The treatment was based on systematical chemotherapy although vulvar lesion has a bad response to chemotherapy. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
