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扇贝来源碳量子点性质及其与镉的联合毒性
引用本文:王庆红,谭明乾,齐子和,王海涛. 扇贝来源碳量子点性质及其与镉的联合毒性[J]. 食品科学, 2021, 42(5): 169-176. DOI: 10.7506/spkx1002-6630-20200226-290
作者姓名:王庆红  谭明乾  齐子和  王海涛
作者单位:(1.大连工业大学食品学院,辽宁 大连 116034;2.国家海洋食品工程技术研究中心,辽宁 大连 116034)
基金项目:“十三五”国家重点研发计划重点专项(2017YFC1600702)。
摘    要:食品加工过程中形成的碳量子点(carbon quantum dots,CQDs)可能导致潜在的健康风险.为系统考察来源于虾夷扇贝(Patinopecten yessoensis)的CQDs,对扇贝来源CQDs分别进行透射电子显微镜观察、X射线光电子能谱分析、傅里叶变换红外光谱分析、等温滴定量热分析以及细胞毒性评价.透射...

关 键 词:碳量子点    扇贝  联合毒性

Characterization of Carbon Quantum Dots from Boiled Scallop(Patinopecten yessoensis)and Its Combined Toxicity with Cadmium
WANG Qinghong,TAN Mingqian,QI Zihe,WANG Haitao. Characterization of Carbon Quantum Dots from Boiled Scallop(Patinopecten yessoensis)and Its Combined Toxicity with Cadmium[J]. Food Science, 2021, 42(5): 169-176. DOI: 10.7506/spkx1002-6630-20200226-290
Authors:WANG Qinghong  TAN Mingqian  QI Zihe  WANG Haitao
Affiliation:(1. School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China; 2. National Engineering Research Center of Seafood, Dalian 116034, China)
Abstract:Carbon quantum dots(CQDs)formed during food processing may cause potential health risks.In this study,CQDs from boiled scallop were characterized systematically.The CQDs were roughly spherical in appearance and well dispersed as observed in transmission electron microscopic images.The average diameter of the CQDs was around 3.7 nm.The presence of hydroxyl,amino,and carboxyl groups on the CQDs surface was demonstrated by Fourier transform infrared and X-ray photoelectron spectroscopy.The interaction of the CQDs with cadmium was investigated by isothermal titration calorimetry(ITC),and the results revealed electrostatic interaction to be the predominant driving force for the binding between cadmium and the CQDs.In addition,the combined toxicity of the CQDs and cadmium was investigated.The results suggested combination with the CQDs increased the toxicity of cadmium by enhancing reactive oxygen species production and mitochondrial membrane damage,disturbing the cell cycle.This study provides useful information for understanding the properties of foodborne nanoparticles.
Keywords:carbon quantum dots  cadmium  scallop  combined toxicity
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