超高效液相色谱法测定卷烟包装纸中的甲醛和乙醛

研究了超高效液相色谱用于卷烟包装纸中甲醛和乙醛含量测定方法。甲醛和乙醛通过2,4-二硝基苯肼衍生化后,以0.5%甲酸水溶液-乙腈(体积比为65∶35)为流动相,在Waters BEHShield RP18(1.7μm,2.1 mm×50 mm)色谱柱上分离,二极管阵列检测器检测,检测波长360 nm。甲醛和乙醛在5 min内即可完全分离,方法具有较好的重现性和线性关系,相关系数均达到0.999 9,加标回收率甲醛为97.9%,乙醛为95.5%;用于卷烟包装纸中甲醛和乙醛的快速测定,结果满意。

Determination of Formaldehyde and Acetaldehyde in Cigarette Wrapping Paper by UPLC

An ultra performance liquid chromatographic （UPLC） method for determination of formaldehyde and acetaldehyde in cigarette wrapping paper was studied. The formaldehyde and acetaldehyde were derivatizated with 2,4-dinitrophenylhydrazine, then they were separated by Waters BEH ShieldRP18 column with 0.5% formic acid and acetonitrile （65：35, v/v） as mobile phase and detected with photodiode array detecter （PDA） at 360 nm. The formaldehyde and acetaldehyde were completely separated and detected in 5 min. The method has good repeatability and linearity. All the correlation coefficients are above 0. 9999. Their recoveries were 97.9% and 95.5% respectively. The method was satisfied with the results by rapid determination of formaldehyde and acetaldehyde in cigarette wrapping paper.