In vitro selection of phosphorothiolated aptamers |
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Authors: | S Jhaveri B Olwin AD Ellington |
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Affiliation: | Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA. |
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Abstract: | A pool of RNA molecules that contained exclusively phosphorothioate internucleoside linkages was used as a starting point for the selection of aptamers that bind to basic fibroblast growth factor (bFGF), and appear to act as heparin mimics. |
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