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食物基质和胃肠道对经口暴露纳米颗粒物理化学性质和生物效应的影响
引用本文:徐斐,姜昆,黎燕,曹慧,袁敏,叶泰,于劲松,阴凤琴,吴秀秀,郝丽玲. 食物基质和胃肠道对经口暴露纳米颗粒物理化学性质和生物效应的影响[J]. 食品与生物技术学报, 2021, 40(8): 17-26
作者姓名:徐斐  姜昆  黎燕  曹慧  袁敏  叶泰  于劲松  阴凤琴  吴秀秀  郝丽玲
作者单位:上海理工大学 医疗器械与食品学院/上海食品快速检测工程技术研究中心,上海 200093
摘    要:食品中纳米颗粒的增加使得其经口暴露于人体的可能性增大.因此,准确评估经口暴露纳米颗粒安全性十分重要.作者综述了食品中最常见纳米颗粒与食物基质、胃肠道的相互作用对纳米颗粒物理化学性质和生物效应影响,为准确评估纳米颗粒安全性提供参考.

关 键 词:纳米颗粒  食物基质  相互作用  安全性

Effects of Food Matrix and Gastrointestinal Tract on Physicochemical Properties and Biological Responses of Nanoparticles by Oral Ingestion
XU Fei,JIANG Kun,LI Yan,CAO Hui,YUAN Min,YE Tai,YU Jinsong,YIN Fengqin,WU Xiuxiu,HAO Liling. Effects of Food Matrix and Gastrointestinal Tract on Physicochemical Properties and Biological Responses of Nanoparticles by Oral Ingestion[J]. Journal of Food Science and Biotechnology, 2021, 40(8): 17-26
Authors:XU Fei  JIANG Kun  LI Yan  CAO Hui  YUAN Min  YE Tai  YU Jinsong  YIN Fengqin  WU Xiuxiu  HAO Liling
Affiliation:School of Medical Instrument and Food Engineering / Shanghai Engineering Research Center for Food Papid dtection, University of Shanghai for Science and Technology, Shanghai 200093, China
Abstract:The increase of nanoparticles in food enhances the exposure possibility of human to nanoparticles by oral ingestion. Therefore, it is very important to accurately assess the safety of orally ingested nanoparticles. This review summarized the effects of the interaction of common nanoparticles in food with food matrices and gastrointestinal tract on the physicochemical properties and biological responses of nanoparticles, providing a reference for an accurate safety assessment of nanoparticles.
Keywords:nanoparticles   food matrices   interaction   safety
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