Antioxidant activity and chemical constituents of essential oil and extracts of Rhizoma Homalomenae |
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Authors: | Ling-Bin Zeng Zhong-Rong Zhang Zhu-Hua Luo Ji-Xiao Zhu |
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Affiliation: | 1. Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Hong Kong SAR, China;2. Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, Xiamen 361005, Fujian, China;3. College of Pharmaceutical Science, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi, China |
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Abstract: | Antioxidant activity and composition of essential oil and extracts of Rhizoma Homalomenae were determined. The extracts, especially the ethyl acetate extract (QJ4 fraction) of the aqueous residue after oil distillation, had considerable antioxidant potency which was significantly associated with their total phenolic and flavonoid contents, but the essential oil showed only weak or moderate activity. GC–MS analysis of the essential oil (yield: 0.82%, v/w) resulted in the identification of 77 compounds, accounting for 96.5% of the content of the oil. The major components, epi-α-cadinol (14.8%), α-cadinol (14.8%), α-terpineol (13.8%), linalool (11.1%), terpinen-4-ol (4.92%), and δ-cadinene (4.91%) constituted 64.3% of it. LC–MS/MS and HPLC analyses showed seven phenolic compounds (protocatechuic acid, vanillic acid, syringic acid, caffeic acid, p-coumaric acid, ferulic acid and apigenin) with a great amount in the ethyl acetate extract (QJ4 fraction). The strong antioxidant properties of the plant extracts may be attributed to the presence of these phenolics. |
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Keywords: | Homalomena occulta Rhizoma Homalomenae Antioxidant activity Essential oil GC&ndash MS LC&ndash MS/MS HPLC |
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