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环境样品中药物和个人护理品的分析检测方法
引用本文:杨林,李科林,赵高峰,吴正勇,李昆,宋津京.环境样品中药物和个人护理品的分析检测方法[J].中国石油和化工标准与质量,2011,31(5).
作者姓名:杨林  李科林  赵高峰  吴正勇  李昆  宋津京
作者单位:1. 中南林业科技大学,湖南,长沙,410004
2. 中国水利水电科学研究院,北京,100038
摘    要:采用固相萃取技术对样品进行预处理,建立了对优化的药物与个人物理品的LC/MS分析方法.本方法的分析灵敏度高,可对多种目标化合物同时分析测定,其最低检测限(LOD)在10-40ng/L。该方法对替代物的平均回收率是89.81%。液相色谱质谱由于不需要衍生化在环境药物及个人护理品的分析中得到广泛的应用,开发对多种物质同时识别并具有良好的灵敏性和选择性的分析方法是今后的研究方向。

关 键 词:药物与个人护理品  固相萃取  超声溶剂萃取  高效液相色谱/质谱

Environmental samples of Pharmaceutical and personal care products in the analysis and detection methods
YANG Lin,LI Ke-lin,ZHAO Gao-feng,WU Zheng-yong,LI Kun,SONG Jin-jing.Environmental samples of Pharmaceutical and personal care products in the analysis and detection methods[J].China Petroleum and Chemical Standard and Quality,2011,31(5).
Authors:YANG Lin  LI Ke-lin  ZHAO Gao-feng  WU Zheng-yong  LI Kun  SONG Jin-jing
Abstract:Solid phase extraction sample pretreatment technique,the establishment of a drug on the optimization of physical goods and personal LC / MS analysis.The method of high sensitivity and simultaneous analysis of multiple target compounds measured,the minimum detection limit(LOD) in the 10-40ng / L.This method substitutes the average recovery rate was 89.81%.Liquid chromatography mass spectrometry in the environment because no dramatization of Pharmaceutical and personal care products are widely used in the analysis,development of a variety of substances at the same time identify and has a good sensitivity and selectivity of analysis is the direction of future research.
Keywords:Pharmaceutical and personal care products  Solid Phase Extraction  Ultrasonic Solvent Extraction  High Performance Liquid Chromatography-Mass
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