| 苯氧菌酯的合成研究 |
| |
| 引用本文： | 刘卫东,徐道庄,杜升华,吴光群.苯氧菌酯的合成研究[J].精细化工中间体,2003,33(4):10-11. |
| |
| 作者姓名： | 刘卫东 徐道庄 杜升华 吴光群 |
| |
| 作者单位： | 湖南化工研究院,湖南,长沙,410007 |
| |
| 摘 要： | 以苯酞和邻甲酚为起始原料 ,生成物经酰氯化、酰氰化、水解反应得苯基草酸甲酯衍生物 ,再与甲氧基氨盐酸反应得Z/E构型混合物。该混合物经转位反应得苯氧菌酯。反应总收率为 5 7 2 % (以苯酞计 ) ,产品纯度为 95 %。该工艺流程简单 ,易于工业化生产
|
| 关 键 词： | 苯氧菌酯 邻甲酚 苯酞 合成 |
| 文章编号： | 1009-9212(2003)04-0010-02 |
| 修稿时间： | 2003年5月8日 |
The Synthesis Study on Kresoxim-methyl |
| |
| LIU Wei,dong etc..The Synthesis Study on Kresoxim-methyl[J].Fine Chemical Intermediates,2003,33(4):10-11. |
| |
| Authors: | LIU Wei dong etc |
| |
| Abstract: | Kresoxim methyl was prepared by reacting the intermediate, methyl 2 (2 methylphenoxymethyl) phenylglyoxylate, with O-methylhydroxylamine hydrochloride. The resulting E/Z isomer mixture was treated with hydrochloride for substantial rearrangement of the Z to the E isomer. The intermediate was synthesized by using O cresol, phthalide, thionyl chloride, and sodium cyanide as raw materials. The total yield of the five steps reaches 57.2% (according to phthalide), and the process is convinient and suitable for the industrial manufacture. |
| |
| Keywords: | Kresoxim-methyl O cresol phthalide synthesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
