Enhanced Bioavailability of Eicosapentaenoic Acid from Fish Oil After Encapsulation Within Plant Spore Exines as Microcapsules |
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Authors: | Ammar Wakil Grahame Mackenzie Alberto Diego-Taboada J Gordon Bell Stephen L Atkin |
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Affiliation: | (1) Hull Royal Infirmary, Michael White Diabetes Centre, 220-236 Anlaby Road, HU3 2RW Hull, UK;(2) Department of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX, UK;(3) Nutrition Group, Institute of Aquaculture, University of Stirling, Stirling, FK9 4LA, UK |
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Abstract: | Benefits of eicosapentaenoic acid (EPA) can be enhanced by raising their bioavailability through microencapsulation. Pollen
can be emptied to form hollow shells, known as exines, and then used to encapsulate material, such as oils in a dry powder
form. Six healthy volunteers ingested 4.6 g of fish oil containing 20% EPA in the form of ethyl ester first alone and then
as 1:1 microencapsulated powder of exines and fish oil. Serum bioavailability of EPA was measured by area under curve (AUC0–24). The mean AUC0–24 of EPA from ethyl ester with exine (M = 19.7, SD = 4.3) was significantly higher than ethyl ester without exines (M = 2, SD = 1.4, p < 0.01).The bioavailability of EPA is enhanced by encapsulation by pollen exines. |
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