| 二萜生物碱它拉乌头胺的结构改造 |
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| 引用本文： | 朱开礼,刘乐燕. 二萜生物碱它拉乌头胺的结构改造[J]. 广州化工, 2011, 39(16): 20-22 |
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| 作者姓名： | 朱开礼 刘乐燕 |
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| 作者单位： | 甘肃民族师范学院化学与生命科学系,甘肃合作,747000 |
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| 摘 要： | 二萜生物碱是一类重要的天然化合物,在具有药性的同时也具有较大的毒性。以二萜生物碱Talatisamine为原料,与一系列的酰氯进行酯化反应,利用现代波谱技术（主要为1HNMR、13CNMR）确定所得产物的结构,共得到了7个非天然二萜生物碱,其中6个为未见文献报道的非天然二萜生物碱。
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| 关 键 词： | 二萜生物碱 结构改造 它拉乌头胺 |
Structural Modification of Diterpenoid Alkaloid Talatisamine |
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| ZHU Kai-li,LIU Le-yan. Structural Modification of Diterpenoid Alkaloid Talatisamine[J]. GuangZhou Chemical Industry and Technology, 2011, 39(16): 20-22 |
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| Authors: | ZHU Kai-li LIU Le-yan |
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| Affiliation: | (College of Chemistry and Life Science,Gansu Normal University for Nationalities,Gansu Hezuo 747000,China) |
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| Abstract: | Diterpenoid alkaloid was an important class of natural compounds that had medicinal properties but aslo had greater toxicity.Some structural modifications were undertaken from talatisamine,which reacted with a series of acyl chlorides.Using madern Pop technology（mainly 1HNMR,13CMMR）,the structure of the product obtained was determined,and seven derivatives were got,in which six of them were unreported diterpenoid alkaloids. |
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| Keywords: | diterpenoid alkaloid structural modification talatisamine |
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