| 羟基磷灰石对硅橡胶复合材料抗凝血性能的影响 |
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| 引用本文： | 牟善松,屠美,汤顺清,周长忍. 羟基磷灰石对硅橡胶复合材料抗凝血性能的影响[J]. 材料科学与工程学报, 2003, 21(2): 162-164 |
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| 作者姓名： | 牟善松 屠美 汤顺清 周长忍 |
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| 作者单位： | 暨南大学生物医学工程研究所,广州,510632 |
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| 摘 要： | 本研究制备了在165℃×10min条件下交联的机械共混羟基磷灰石和硅橡胶生物材料,并通过动态凝血试验、溶血率测定、血小板粘附的SEM观察等方法评价了羟基磷灰石与硅橡胶复合材料的血液相容性.结果表明,含60%羟基磷灰石的复合材料血液相容性最佳.
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| 关 键 词： | 羟基磷灰石 硅橡胶 血液相容性 医用生物材料 复合材料 抗凝血性能 |
Effect of Hydroxyapatite on the Blood Compatibility of Silicone Rubber Composite Materials |
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| Abstract. Effect of Hydroxyapatite on the Blood Compatibility of Silicone Rubber Composite Materials[J]. Journal of Materials Science and Engineering, 2003, 21(2): 162-164 |
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| Authors: | Abstract |
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| Abstract: | Hydroxyapatite( HA)/ silicone rubber (SR) composite material was suggested to be used as biomaterials.In this paper, HA and SR were mixed by machine, and then crosslinked on the press vulcanizer at 165℃ for 10min. The relationship between the HA content in composite materials and blood compatibility was identified by the dynamic blood-clotting tests, haemolysis ratio measurement, platelet adhesion and SEM observation. The results show that the blood-compatibility of composite membranes with the concentration of HA 60% (wt) is more excellent than that of other HA/SR composite materials. |
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| Keywords: | hydroxyapatite silicone bloodcompatibility |
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