果糖/对甲基苯磺酸磺化炭催化合成芳香醛肟的研究

以果糖/对甲基苯磺酸磺化炭为催化剂,在水溶液中能高效、高选择性合成芳香醛肟。考察了催化剂用量及种类、溶剂种类和反应温度等因素对反应产率的影响,研究了不同结构芳香醛底物对反应的容忍性,同时对催化剂的重复使用率进行了评价,并通过熔点测定和1H NMR等手段对产物结构进行表征。实验结果表明：m磺化炭∶m苯钾醛为0.1%,以水/甲醇（体积比5∶1）为溶剂,反应温度在100℃回流时,芳香醛肟的产率达到73%-97%。磺化炭在反应中具有良好的稳定性,重复使用3次,反应产率基本保持不变。该催化体系不仅对环境无污染,而且条件温和,反应时间短,效率高。

Synthesis of Benzaldoxime Catalyzed with Sulfonated Carbon from Fructoe/TsOH

Benzaldoxime was efficiently and selectively synthesized in hydrophilic solvent with sulfonated carbon catalyst from fructose / Ts OH. The effects of sorts and amounts of catalysts,solvents and reaction temperature on the yields were investigated,the influence of structure of substrate on the reaction tolerance was researched,and the recyclability of catalyst was evaluated as well. The structures of products were characterized by melting points and NMR. The results showed that the yield of benzaldoxime was 75% - 95% under the optimum conditions that the mass ration of sulfonated carbon and benzaldehyde was 0. 1%,solvent was water / methanol（ volum ratio was 5 ∶1） and temperature was 100 ℃under refluxed. Sulfonated carbon catalyst had a good stability and can be reused for 5 times in the reaction with approximatly constant yields. This catalytic system had advantages of a simple operation,short reaction time,high conversion and less pollution to environment.