氧乐果原药中主要杂质的GC/MS定性分析

利用气相色谱-质谱联用仪对氧乐果原药中所含主要杂质进行了定性分析，据GC／MS结果和氧乐果生产工艺推断其两种主要杂质为O，O-二甲基亚磷酸酯和O，O-二甲基-S-(甲氧基羰基甲基)硫代磷酸酯，合成杂质标样，由保留时间及质谱图确证了推断的杂质组成和结构，推测其质谱裂解途径，为氧乐果的分析及生产提供依据。

Identification of the Primary Impurities in Omethoate Technical by GC/MS

The primary impurities contained in omethoate technical were identified by gas chromatography coupled with mass spectrometry (GC/MS). From GC/MS results along with the process used to manufacture omethoate, it was concluded that the two main impurities were dimethyl phosphite and O,O-dimethyl-S-(methoxycarbonylmethyl) phosphorothioate. Samples of the impurities were synthesized and their composition and structure confirmed by retention time and the mass spectra output. A possible mass spectra fragmentation pathway is proposed. These results provide a basis for omethoate production and analysis.