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Dietetic and hypocholesterolaemic action of black soy peptide in dietary obese rats
Authors:Shin Joung Rho  Soojin Park  Chang‐Won Ahn  Jae‐Kil Shin  Hyeon Gyu Lee
Affiliation:1. Department of Food and Nutrition, Hanyang University, Seoul, Korea;2. SJ Rho and S Park contributed equally to this work.;3. Ginseng Research Group, Korea Food Research Institute, Kyunggi‐Do, Korea;4. Research and Development Center, Nong Shim Co., Ltd, Kyunggi‐Do, Korea
Abstract:To investigate the effect of peptides from black soy (rat's eye) bean (Rhynchosia volubilis Lour.) on weight gain and lipid composition, Sprague–Dawley male rats were fed either a black soy peptide (BSP; 2, 6 or 10% of energy)‐containing diet or a casein control diet (20% of energy) enriched with 36% fat and 1% cholesterol for 28 days. Compared with the casein group, the BSP groups showed significant attenuation of body, liver and epididymal adipose tissue weight gains (P < 0.05). Moreover, rats that consumed BSP had a lower total cholesterol concentration and low‐density lipoprotein/high‐density lipoprotein (LDL/HDL) ratio in serum and a lower level of hepatic triglycerides as well as higher excretion of faeces compared with those fed only casein (P < 0.05). Molecular weights of peptides from black soy were mainly below 10 kDa, and Arg/Lys and Gly/Met ratios in BSP were five and three times of those in casein respectively. It is concluded that BSP can be a potent nutraceutical component for anti‐obesity and hypolipidaemic benefits. Copyright © 2007 Society of Chemical Industry
Keywords:black soy peptide  obesity  weight loss  lipid profile  cholesterol
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