| 降解法制备聚己内酯-聚乙二醇两亲性共聚物纳米胶束 |
| |
| 引用本文： | 潘光耀,倪才华. 降解法制备聚己内酯-聚乙二醇两亲性共聚物纳米胶束[J]. 应用化工, 2012, 41(6): 1041-1043,1047 |
| |
| 作者姓名： | 潘光耀 倪才华 |
| |
| 作者单位： | 江南大学食品胶体与生物技术教育部重点实验室,江苏无锡214122;江南大学化学与材料工程学院,江苏无锡214122 |
| |
| 摘 要： | 用降解方法合成了聚己内酯(PCL)与聚乙二醇(PEG)两亲性嵌段聚合物聚己内酯-聚乙二醇(PCL-b-PEG),并制成了胶束溶液。用红外光谱(FTIR)、核磁共振(NMR)、荧光光谱(FS)、纳米粒度仪及透射电镜(TEM)对聚合物胶束进行了表征。结果表明,临界胶束浓度(CMC)随着聚合物分子量的增大而减小,胶束粒径随着共聚物中聚己内酯含量的增大而增大。用热重分析(TGA),差热方法(DSC)分析了该双亲性嵌段共聚物的热学性能。此方法合成胶束,步骤简单、成本低廉、胶束粒径分布较窄。
|
| 关 键 词： | 聚己内酯 聚乙二醇 胶束 降解 |
Preparation of amphiphilic polycaprolactone-block-polyglycol copolymer nano micelles by degradation method |
| |
| PAN Guang-yao , NI Cai-hua. Preparation of amphiphilic polycaprolactone-block-polyglycol copolymer nano micelles by degradation method[J]. Applied chemical industry, 2012, 41(6): 1041-1043,1047 |
| |
| Authors: | PAN Guang-yao NI Cai-hua |
| |
| Affiliation: | 1,2(1.The Key Laboratory of Food Colloids and Biotechnology,Ministry of Education,Jiangnan University,Wuxi 214122, China;2.School of Chemical and Material Engineering,Jiangnan University,Wuxi 214122,China) |
| |
| Abstract: | Amphiphilic block copolymer of polycaprolactone-block-polyglycol was synthesized via degradation method and micellar solution was obtained.Fourier transform infrared(FTIR),nuclear magnetic resonance(NMR),fluorescence spectrum(FS),nanoparticle size analyze and transmission electron microscope(TEM) measurement were conducted.The results showed that the critical micell concentration(CMC)decreased as the molecular weight increased,and the micelle size increased as the polycaprolactone(PCL) content increased.The thermal properties of the copolymer were studied by TGA and DSC.The method is simple,cost-efficient and the products have narrow size distribution. |
| |
| Keywords: | polycaprolactone polyglycol micelle degradation |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
