| 造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨 |
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| 引用本文： | 孙慧斌,刘及,李荣贵. 造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨[J]. 辐射研究与辐射工艺学报, 1989, 0(3) |
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| 作者姓名： | 孙慧斌 刘及 李荣贵 |
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| 作者单位： | 白求恩医科大学 长春(孙慧斌，刘及)，白求恩医科大学 长春(李荣贵) |
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| 摘 要： | 本文依据集落细胞密度进行了豚鼠骨髓CFU-f的剂量—存活曲线测定。结合有关放射生物学资料的分析和集落形态观察,证明该CFU-f为非均一性群体,可区分为致密型(D_0=2.17 Gy,N=1.14)和疏松型(D_0=4.09 Gy,N=1.13)等两个放射敏感性不同的亚群。这一结果对于加深理解CFU-f的放射生物学特性和放射损伤与修复规律,探讨CFU-f的亚群分类有着重要意义。
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| 关 键 词： | CFU-f 放射敏感性 CFU-f亚群 |
AN APPROACH OF RADIOSENSITIVITY OF THE CFU-F IN THE BONE MARROW AND ITS SUBPOPULATION CLASSIFICATION |
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| Sun Huibin,Liu Ji,Li Ronggui Norman Bethune University of Medical Sciences,Changchun. AN APPROACH OF RADIOSENSITIVITY OF THE CFU-F IN THE BONE MARROW AND ITS SUBPOPULATION CLASSIFICATION[J]. Journal of Radiation Research and Radiation Processing, 1989, 0(3) |
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| Authors: | Sun Huibin Liu Ji Li Ronggui Norman Bethune University of Medical Sciences Changchun |
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| Abstract: | The cell survival curve of the CFU-f in the guinea-pig bone mar-row, which is distinguished according to the cellular density of colony, is assayed.By the analysis of the relative data from the experiment and the observation of themorphology of colony. we have proved that there are two distinct subpopulationsin radiosensitivity and colonial morphology among the CFU-f populations in the gui-nea-Dig bone marrow. The dense cellular colony type subpopulation of the CFU-f:D_0=2. 17 Gy, N=1. 14; the sparse cellular colony type subpopulation of the CFU-f:D_0=4. 09 Gy, N=1. 13. The studies may have important implication in acquiring abetter understanding of the characteristics of the radiation biology as well as the ruleof the radiation injury and recovery of the CFU-f. |
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| Keywords: | CFU-f Radiosensitivity Subpopulation |
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