| 加压微波辅助水解甘草酸粗品制备甘草次酸(英文) |
| |
| 引用本文： | 王仁敏,林婵,刘晶靓,余方,高建培,潘学军.加压微波辅助水解甘草酸粗品制备甘草次酸(英文)[J].中国化学工程学报,2012,20(1):152-157. |
| |
| 作者姓名： | 王仁敏 林婵 刘晶靓 余方 高建培 潘学军 |
| |
| 作者单位： | Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China |
| |
| 基金项目： | Supported by the Yunnan Provincial Department of Education Key Foundation (07Z10311) |
| |
| 摘 要： | A pressured microwave-assisted hydrolysis(PMAH) technique has been developed for hydrolyzing the crude glycyrrhizic acid(GA) extracted from licorice root to prepare glycyrrhetinic acid(GRA).In order to optimize the efficiency of PMAH,several experimental parameters were investigated,including liquid-solid ratio,hydrolysis time,sulfuric acid concentration and hydrolysis temperature.The optimized hydrolysis conditions were as follows:pressured microwave-assisted hydrolysis of crude GA for 21 min(taking 15 min to reach 150 oC,and holding it for 6 min) at 150 oC(at a radiation power of 450 W) in 3%-5% sulfuric acid solution with the liquid-solid(ml?g?1 crude GA) ratio of 25︰1.As a result of the considerable saving in time and higher product yields(up to 90%),PMAH was proved more effective than conventional methods.
|
| 关 键 词： | glycyrrhetinic acid glycyrrhizic acid licorice root pressured microwave-assisted hydrolysis high performance liquid chromatography |
| 收稿时间： | 2011-05-20 |
Pressured Microwave-assisted Hydrolysis of Crude Glycyrrhizic Acid for Preparation of Glycyrrhetinic Acid |
| |
| WANG Renmin,LIN Chan,LIU Jingliang,YU Fang,GAO Jianpei and PAN Xuejun.Pressured Microwave-assisted Hydrolysis of Crude Glycyrrhizic Acid for Preparation of Glycyrrhetinic Acid[J].Chinese Journal of Chemical Engineering,2012,20(1):152-157. |
| |
| Authors: | WANG Renmin LIN Chan LIU Jingliang YU Fang GAO Jianpei and PAN Xuejun |
| |
| Affiliation: | Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China |
| |
| Abstract: | A pressured microwave-assisted hydrolysis(PMAH) technique has been developed for hydrolyzing the crude glycyrrhizic acid(GA) extracted from licorice root to prepare glycyrrhetinic acid(GRA).In order to optimize the efficiency of PMAH,several experimental parameters were investigated,including liquid-solid ratio,hydrolysis time,sulfuric acid concentration and hydrolysis temperature.The optimized hydrolysis conditions were as follows:pressured microwave-assisted hydrolysis of crude GA for 21 min(taking 15 min to reach 150℃,and holding it for 6 min) at 150℃(at a radiation power of 450 W) in 3%-5% sulfuric acid solution with the liquid-solid(ml·g-1 crude GA) ratio of 25:1.As a result of the considerable saving in time and higher product yields(up to 90%),PMAH was proved more effective than conventional methods. |
| |
| Keywords: | glycyrrhetinic acid glycyrrhizic acid licorice root pressured microwave-assisted hydrolysis high performance liquid chromatography |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国化学工程学报》浏览原始摘要信息 |
|
点击此处可从《中国化学工程学报》下载全文 |
|
