Nano-magnetic-iron Oxides@choline Acetate as a Heterogeneous Catalyst for the Synthesis of 1,2,3-Triazoles

In this research, four cholines supported on core–shell iron oxides, Fe₂O₃@MgO@Ch.OAc (choline acetate), Fe₂O₃@MgO@Ch.OH (choline hydroxide), Fe₃O₄@Ch.OAc, Fe₃O₄@Ch.OH, were synthesized. The synthesized catalysts were tested in 1,2,3-triazoles synthesis by the reaction of nitromethane, aldehyde, and benzyl azide in EtOH as a green solvent. Among four synthesized heterogeneous catalysts, the Fe₂O₃@MgO@ch.OAc showed superior catalytic activity for the reaction and afforded the desired triazoles in good isolated yields under mild reaction conditions.

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