| 钙对高脂膳食小鼠血清抗氧化能力与血脂的影响 |
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| 引用本文： | 肖瀛,杜丹. 钙对高脂膳食小鼠血清抗氧化能力与血脂的影响[J]. 食品工业科技, 2011, 0(11): 387-389,393 |
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| 作者姓名： | 肖瀛 杜丹 |
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| 作者单位： | 1. 上海应用技术学院香料香精技术与工程学院食品系,上海,200235
2. 江阴百泰生物科技有限公司,江苏江阴,214434 |
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| 基金项目： | 上海市教委优青基金(yyy11068); 校科研项目(YJ2011-09) |
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| 摘 要： | 探究了膳食钙水平对饲喂高脂膳食小鼠机体的抗氧化能力与血脂代谢的影响,以及二者之间关系。实验选用5周龄C57BL/6雄性小鼠,随机分为4组（n=10）：对照组、高脂模型组、高脂低钙组、高脂高钙组。饲喂6周,高脂模型组和高脂低钙组小鼠的血浆TG、TC、LDL-C值显著高于对照组,而抗氧化能力指标和脂蛋白酯酶（LPL）活性显著低于对照组（P〈0.05）。高脂高钙组的TG、TC值显著低于高脂模型组,LPL活性和抗氧化能力指标则显著高于高脂模型组。相关性分析表明,总抗氧化能力（T-AOC）与TG（r=-0.976,P=0.012）、TC（r=-0.989,P=0.006）呈现显著的负相关,而与LPL（r=0.945,P=0.028）呈显著正相关。结果表明,高膳食钙可改善高脂膳食性脂代谢紊乱的作用可能与提高机体抗氧化能力有关。
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| 关 键 词： | 血脂代谢紊乱 膳食钙 抗氧化 小鼠 |
Effects of dietary calcium on antioxidant capacity and blood lipid in mice fed high-fat diet |
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| XIAO Ying,DU Dan. Effects of dietary calcium on antioxidant capacity and blood lipid in mice fed high-fat diet[J]. Science and Technology of Food Industry, 2011, 0(11): 387-389,393 |
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| Authors: | XIAO Ying DU Dan |
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| Affiliation: | XIAO Ying1,DU Dan2(1.School of Perfume and Aroma Technology,Shanghai Institute of Technology,Shanghai 200235,China,2.Jiangyin BridgeBio Biotechnology Company,Jiangyin 214434,China) |
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| Abstract: | The aim was to investigate effects of calcium intake levels on blood lipids metabolism and antioxidant capacity in mice fed high-fat diet(HFD)and relation between them.C57BL/6 mice(5 weeks old)were randomly assigned to four groups(n=10).The mice of four groups were fed with normal diet,HFD,HFD with low calcium(LCHFD),and HFD with high calcium(HCHFD),respectively.After 6 weeks feeding,the LCHFD and HFD induced a significant increase in plasma TG,TC and LDL-C and a significant decrease in LPL activity and ant... |
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| Keywords: | dyslipidemia dietary calcium antioxidant mice |
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