| 密螺旋体Reiter株纯化轴丝在梅毒血清学诊断中的应用 |
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| 引用本文： | 张绍枫,王薇媛,辜清吾. 密螺旋体Reiter株纯化轴丝在梅毒血清学诊断中的应用[J]. 中国生物制品学杂志, 1992, 0(2) |
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| 作者姓名： | 张绍枫 王薇媛 辜清吾 |
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| 作者单位： | 中国药品生物制品检定所 北京100050 |
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| 基金项目： | 本试验得到国家自然科学基金资助 |
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| 摘 要： | 本试验以纯化的 Reiter 株轴丝为抗原,建立了 AF-ELISA 试验方法。用该方法检测了35份自家免疫病人血清、285份非梅毒病人血清及78份各期梅毒病人血清,并同时与 FTA-ABS 进行比较,结果 AF-ELISA 特异性为99.3%,FTA-ABS 为99.7%,两者敏感性为100%。
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| 关 键 词： | 轴丝(axial filaments,简称 AF) AF-ELISA FIA-ABS |
The Application of the Purified Axial Filament of the Reiter treponeme in the serodiagnosis of syphilis |
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| Zhang Shaofeng National Institute for the Control of Pharmaceutical and Biological Products,Beijing. The Application of the Purified Axial Filament of the Reiter treponeme in the serodiagnosis of syphilis[J]. Chinese Journal of Bilogicals, 1992, 0(2) |
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| Authors: | Zhang Shaofeng National Institute for the Control of Pharmaceutical Biological Products Beijing |
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| Abstract: | Using the purified axial filaments of the Reiter treponeme,we developed an enzyme-linked immunoabsorbent assay (AF-ELISA) for the serodiagnosis of syphilis.AF-ELISA was comparedwith FTA-ARS using 35 serum samples from patients with autoimmune disease,285 with nonsyphilisand 78 from patients at different stages of syphilis.The specificity of the AF-ELISA and the PTA-ABSwere 99.3% and 99.7% respectively,and the sensitivity of the two methods were both 100%.Theabove results showed that this test night be widely used in the serodiagnosis of syphilis. |
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| Keywords: | Axial Filaments(AF) AF-ELISA FTA-ABS |
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