A new rhodamine-based single molecule multianalyte (Cu, Hg) sensor and its application in the biological system |
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| Authors: | Lina WangJieXi Yan Wenwu QinWeisheng Liu Rui Wang |
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| Affiliation: | a Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China
b Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, School of Life Sciences, and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China |
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| Abstract: | A new single molecule multianalyte sensor, vanillic aldehyde rhodamine 6G hydrazone has been designed for the selective detection of Cu2+ and Hg2+ ions. UV/Vis spectroscopy indicates that the sensor is a good chromogenic chemosensor for Cu2+ in 1:99 (v/v) ethanol-water media. Whereas, other ions, such as Li+, Na+, Mg2+, K+, Ca2+, Cr3+, Mn2+, Fe3+, Co2+, Ni2+, Zn2+, Ag+, Cd2+, Ba2+, Hg2+ and Pb2+ failed to generate a distinct response. Fluorescence spectral data reveals that the sensor is an excellent fluorescent chemosensor for Hg2+ in aqueous ethanol solution and with no fluorescent response toward other ions. The spectroscopic behavior of the sensor in living cells indicated that it can be used for the detection of Cu2+ and Hg2+ in environmental and biological systems. Mechanisms for the high selectivity of the sensor to Cu2+ and Hg2+ are discussed. |
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| Keywords: | Multianalyte sensor Cu2+ Hg2+ Fluorescence Imaging Living cells |
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