Non-antibiotic effects of antibiotics: from side effects to therapeutic uses |
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Authors: | P Roblot B Becq-Giraudon |
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Affiliation: | Service de Médecine Interne et Maladies Infectieuses, CHU La Milétrie, Poitiers, France. |
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Abstract: | Sometimes therapeutic needs to tap drugs side effects of a treatment to show new indications for those drugs. Antibiotics, which are somewhat some often-used drugs, are frequently prescribed in non-infectious pathologies. Some indications are reported in the literature: immunosuppressive or antiinflammatory (disulone, salazopyrine, cotrimoxazole, clofazimine, fusidique acid), small bowel prokinetic action (macrolides), endocrine effects (déméclocycline, kétoconazole), enzymatic effects (rifampicine, cyclines), sclerotherapy (cyclines), pro- or anti-tumoral effects. This incomplete list is growing up every days. |
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