| NKC-9酸性树脂催化合成乳酸乙酯活性研究 |
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| 引用本文： | 祝宝福,解育静,王俊永. NKC-9酸性树脂催化合成乳酸乙酯活性研究[J]. 广州化工, 2010, 38(3): 91-92 |
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| 作者姓名： | 祝宝福 解育静 王俊永 |
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| 作者单位： | 广东药学院中山校区,广东,广州,510006;山西生物应用职业技术学院,生物制药工程系,山西,太原,030031;深圳万乐药业有限公司,广东,深圳,518029 |
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| 摘 要： | 研究NKC-9酸性树脂催化合成乳酸乙酯的新工艺。一定量的乳酸与一定量的乙醇,在NKC-9催化作用下以环己烷为脱水剂,采用回流脱水合成工艺。乳酸0.2mol,催化剂0.7g,环己烷25mL,反应时间为3h,当酸醇摩尔比为1:3时,乳酸转化率达49.5%。NKC-9酸性树脂催化合成乳酸乙酯工艺是快速、节能、环境友好的绿色合成新工艺。
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| 关 键 词： | NKC-9 乳酸乙酯 酯化反应 |
Study on NKC-9 Resin Acid Catalysis Activity on Synthesis of Ethyl Lactate |
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| ZHU Bao-fu,XIE Yu-jing,WANG Jun-yong. Study on NKC-9 Resin Acid Catalysis Activity on Synthesis of Ethyl Lactate[J]. GuangZhou Chemical Industry and Technology, 2010, 38(3): 91-92 |
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| Authors: | ZHU Bao-fu XIE Yu-jing WANG Jun-yong |
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| Affiliation: | ZHU Bao -fu , XIE Yu -jing , WANG Jun -yong ( 1 Zhongshan Campus, Guangdong Pharmaceutical University, Guangdong Guangzhou 510006 ; 2 Department of Biological, Shanxi Biological Vocational Technical College, Shanxi Taiyuan 030031 ; 3 Shenzhen Main Luck Pharmaceuticals Inc. , Guangdong Shenzhen 518029, China) |
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| Abstract: | NKC -9 resin acid heterogeneous catalysis activity on synthesis of ethyl lactate was introduced. The preparation processes were investigated under different conditions. The optimum synthetic conditions were 2g lactic acid, 0. 7g NKC -9, 25mL cyclohexane, and reaction time 3h. The molar ratio of lactic acid to ethanol was 1 ： 3, and the yield of the new process was 49.5%. The new developed technology was rapid, economical, green and environmental friendly. |
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| Keywords: | NKC-9 |
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