Functional activity of the thymus gland and pituitary-adrenal system in patients with malignant skin melanoma

Essential changes in the thymus functional condition and hypophyseal-adrenal system were revealed in patients with skin melanoma. The secretory activity of the thymus loosens, and there is a reduction of thymic hormone titer in blood. The increased levels of ACTH and hydrocortisone in blood indicate an enhanced activity of the hypophyseal-adrenal system under this pathology.