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玉米低聚肽中焦谷氨酰亮氨酸(pEL)二肽的研究
引用本文:陈亮,王雨晴,冀峰,李月琪,马勇,谷瑞增. 玉米低聚肽中焦谷氨酰亮氨酸(pEL)二肽的研究[J]. 食品与发酵工业, 2021, 0(3): 49-52
作者姓名:陈亮  王雨晴  冀峰  李月琪  马勇  谷瑞增
作者单位:中国食品发酵工业研究院有限公司;岛津企业管理(中国)有限公司
基金项目:十三五国家重点研发计划项目(2016YFD0400604);国家自然科学基金项目(31671963);北京市科技创新基地培育与发展工程专项(Z191100002819001)。
摘    要:考察了玉米低聚肽的理化组成成分,由于制备玉米低聚肽的原料玉米蛋白氨基酸序列独特,含有较多的谷氨酰胺及亮氨酸,且大多以相邻的位置存在,研究重点考察了玉米低聚肽中具有抗抑郁活性的肽段焦谷氨酰亮氨酸(pyroGlu-Leu,pEL)二肽结构.结果表明,玉米低聚肽蛋白含量高,干基蛋白含量为87.70%,肽含量为82.76%,平...

关 键 词:玉米低聚肽  抗抑郁  焦谷氨酰亮氨酸

Study on pEL dipeptide in corn oligopeptides
CHEN Liang,WANG Yuqing,JI Feng,LI Yueqi,MA Yong,GU Ruizeng. Study on pEL dipeptide in corn oligopeptides[J]. Food and Fermentation Industries, 2021, 0(3): 49-52
Authors:CHEN Liang  WANG Yuqing  JI Feng  LI Yueqi  MA Yong  GU Ruizeng
Affiliation:(Beijing Engineering Research Center of Protein and Functional Peptides,China National Research Institute of Food and Fermentation Industries Co.,Ltd.,Beijing 100015,China;Shimadzu(China)Co.,Ltd.,Beijing 100020,China)
Abstract:The physical and chemical composition of corn oligopeptides was investigated in this study.Due to the unique amino acid sequence of corn protein which with high amount of glutamine and leucine and exist in adjacent positions,this study also focused on the pyroglutamyl-leucine(pyroGlu-Leu,pEL)dipeptide structure with antidepressant activity from corn oligopeptide.The results showed that corn oligopeptide had high protein content which reached 87.70%,and the peptide content was 82.76%.The average molecular weight was 461.20 Da and mainly in the range of 140-1000 Da.The highest content of all amino acids was glutamic acid(glutamine)which reached 21.76%,followed by leucine with a content of 12.79%and leucine was the highest essential amino acid.The results of structural studies indicated that the content of pEL was more than 0.58%in corn oligopeptides,and it was stable in five batches of corn oligopeptide samples.This research provides a theoretical basis for developing corn oligopeptide as a new functional food.
Keywords:corn oligopeptide  antidepressant  pyroGlu-Leu
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