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光动力治疗药物合成进展
引用本文:杨琛. 光动力治疗药物合成进展[J]. 广州化工, 2012, 40(12): 52-54
作者姓名:杨琛
作者单位:中南大学化学化工学院,湖南长沙,410083
摘    要:光动力疗法(Photodynamic Therapy,PDT)是利用光敏剂发生光动力反应进行疾病诊断和治疗的一种新技术。光敏剂经历了第一代光敏剂卟啉及其衍生物、第二代光敏剂酞菁类化合物以及第三代光敏剂,已经逐步走向成熟。本文主介绍了这三代光敏剂的性质及合成。

关 键 词:光动力疗法  光敏剂  合成过程

Progress in the Synthesis of Photodynamic Therapy Drugs
YANG Chen. Progress in the Synthesis of Photodynamic Therapy Drugs[J]. GuangZhou Chemical Industry and Technology, 2012, 40(12): 52-54
Authors:YANG Chen
Affiliation:YANG Chen(College of Chemistry and Chemical Engineering,Central South University, Hunan Changsha 410083,China)
Abstract:Photodynamic Therapy(PDT) was a new technology for disease diagnosis and treatment with photosensitizer conducting photodynamic reaction.Photosensitizer was gradually matured through the first-generation photosensitizers-porphyrin and its derivatives,second-generation photosensitizer-phthalocyanine compounds,as well as third-generation photo-sensitizer.The property and synthesis of the three generations of photosensitizers were described.
Keywords:photodynamic therapy  photosensitizers  synthesis process.
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