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| 核酸适配体在光生化检测中的应用 | |
| 引用本文： | 李瑜,王源升,于斌,张静秋,董瑞.核酸适配体在光生化检测中的应用[J].广州化工,2012,40(14):1-3. |
| 作者姓名： | 李瑜 王源升 于斌 张静秋 董瑞 |
| 作者单位： | 1. 海军工程大学理学院,湖北武汉,430033 2. 海军工程大学训练部,湖北武汉,430032 3. 中国人民解放军海军91315部队,辽宁大连,116041 |
| 摘 要： | 核酸适配体是一小段经体外筛选得到的寡核苷酸序列，能与相应的配体进行高亲和力和强特异性的结合。本文根据核酸适配体在检测靶物质时获得光信号的机理，将核酸适配体在光生化的检测方法进行分类，并评述了‘这些检测方法的优缺点及核酸适配体在生物检测中的发展前景。 |
| 关 键 词： | 核酸适配体 荧光信号 检测 |
Advance in Aptamer -based Optical Detection Research |
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| LI Yu,WANG Yuan-sheng,YU Bin,ZHANG Jing-qiu,DONG Rui.Advance in Aptamer -based Optical Detection Research[J].GuangZhou Chemical Industry and Technology,2012,40(14):1-3. | |
| Authors: | LI Yu WANG Yuan-sheng YU Bin ZHANG Jing-qiu DONG Rui |
| Affiliation: | 1 College of Science,Naval University of Engineering,Hubei Wuhan 430033; 2 Department of Training,Naval University of Engineering,Hubei Wuhan 430033; 3 Naval 91315 Unit of the PLA,Liaoning Dalian 116041,China) |
| Abstract: | Aptamer was a kind of synthetic oligonucleotides discriminated by in vitro screening,which was of high affinity and specificity with its ligands.The detection methods were classified according to their mechanism to obtain optical signals in the detection of target materials.The advantages and shortcomings and development trend of aptamer-based optical biochemical probes were reviewed. |
| Keywords: | aptamer fluorescent signal detection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |